MetaMorph (Molecular Devices)

The MetaMorph Microscopy Automation & Image Analysis Software of the Meta Imaging Series from Molecular Devices is the industry standard for automated microscopy acquisition, device control and image analysis.

With the device control, dissimilar fluorescent microscope hardware and peripherals can be integrated into a single custom workstation easily. Each custom system can be uniquely suited for virtually any experimental paradigm. System integration is made even easier by supporting all major brands of automated microscopes and scientific CCD cameras. This means MetaMorph Software can be used as a common software platform within a core facility or laboratory minimizing maintenance, training, and support of customers and end-users.

Acquiring the image is only the first step of image analysis. MetaMorph image analysis software provides all the tools needed to perform meaningful analysis of acquired images, such as  common tools for thresholding, filtering, and feature extraction as well as more sophisticated tools like the integrated morphometry analysis (IMA) module. IMA allows objects to be measured and separated into user-definable classes, based on any combination of measured morphometric parameters, such as shape, size, or optical density. MetaMorph Software also offers many user-friendly application modules for biology-specific analysis such as cell signaling, cell counting, and protein expression.

Automation of complex, multi-parametric experimental protocols - often the hardest task with any imaging system - is handled elegantly by the MetaMorph Software due to its multi-dimensional aquisition (MDA) module. MDA guides the user through the setup of each acquisition dimension (time, z, fluorescent channels, stage position). Once a particular acquisition is completed through the MDA interface, all settings can be stored and recalled for later use making it easy to perform repeated operations. For those who want to further automate acquisition, processing, and analysis routines, MetaMorph Software features sophisticated and powerful macros called journals. Journals record and save a series of tasks without the need for programming. A graphical editor allows for easy creation and editing of journals using a drag-and-drop interface.

MetaMorph Software is a modular platform that allows you to select only the components you need. Modules are available for:

•    Camera control and acquisition
•    Microscope automation and control
•    Sample positioning and specimen illumination
•    Application modules to make complex, repetitive tasks easier to perform

http://www.moleculardevices.com/Products/Software/Meta-Imaging-Series/MetaMorph.html